Advances in E.coli
Using Thermo Scientific LTQ Orbitrap mass spectrometry technology, HPA researchers have identified the protein toxins expressed by the deadly strain, which has resulted in 37 deaths and made nearly 3,400 people ill.
"The significance of this study is that scientists were able to develop techniques to study microorganisms and determine how the genetic code is being translated into the protein building blocks that determine traits such as toxicity," said Dr Ian Jardine, vice president, global research and development, Thermo Fisher Scientific.
"Our leading Orbitrap mass spectrometry system is enabling researchers to understand what makes this E.coli strain so devastating, and may lead to an improved understanding of how to treat patients."
The technology enabled scientists to identify and analyse the protein fingerprint of this new strain of E.coli using a proteomic. Understanding the organism's ability to produce toxins and other proteins present in this specific strain may reduce the risk to human health and provide more effective treatment options.
Thermo Fisher Scientific: 01509 555500
